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Although several agents have entered clinical evaluation, translation into durable clinical benefit remains challenging due to intratumoral heterogeneity, temporal fluctuations in oxygenation (cycling hypoxia), and adaptive resistance mechanisms that bypass single-pathway inhibition

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After single IM administration at doses of 6, 30, or 150 g/kg, the T max values of each dose were 6.33, 8.67, and 8.17 min, respectively

Ashwagandha Ashwagandha ( Withania somnifera ) has been used in Ayurvedic and indigenous medical systems for over 3,000 years and has been examined in research studies for its stress-lowering effects